Cheng-Chi Chang Selected Research

Proteins (Proteins, Gene)

1/2017	CCN Detection of Cancer Tissues by Immunohistochemistry Staining.
7/2013	Connective tissue growth factor activates pluripotency genes and mesenchymal-epithelial transition in head and neck cancer cells.
8/2011	HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma.
5/2011	Connective tissue growth factor acts as a therapeutic agent and predictor for peritoneal carcinomatosis of colorectal cancer.
11/2008	Connective tissue growth factor (CTGF) and cancer progression.
10/2008	Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.
10/2008	RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma.
6/2008	Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.
7/2006	Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis.
3/2004	Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis.

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Cheng-Chi Chang Research Topics

Disease

29	Neoplasms (Cancer) 01/2016 - 03/2004
14	Neoplasm Metastasis (Metastasis) 01/2017 - 03/2004
10	Squamous Cell Carcinoma of Head and Neck 04/2017 - 09/2010
9	Stomach Neoplasms (Stomach Cancer) 01/2017 - 08/2005
7	Hypoxia (Hypoxemia) 03/2017 - 07/2006
6	Colorectal Neoplasms (Colorectal Cancer) 04/2017 - 01/2005
5	Lung Neoplasms (Lung Cancer) 01/2017 - 01/2004
3	Breast Neoplasms (Breast Cancer) 01/2017 - 06/2004
3	Lymphatic Metastasis 02/2015 - 02/2009
3	Head and Neck Neoplasms (Head and Neck Cancer) 07/2013 - 09/2010
3	Adenocarcinoma of Lung 07/2006 - 01/2004
2	Inflammation (Inflammations) 03/2017 - 10/2008
2	Mouth Neoplasms (Oral Cancer) 01/2017 - 08/2011
2	Colonic Neoplasms (Colon Cancer) 12/2016 - 09/2016
2	Urinary Bladder Neoplasms (Bladder Cancer) 05/2014 - 09/2011
2	Basal Cell Carcinoma (Rodent Ulcer) 11/2013 - 02/2009
2	Disease Progression 03/2013 - 04/2011
2	Experimental Arthritis 03/2013 - 04/2011
2	Arthritis (Polyarthritis) 03/2013 - 04/2011
2	Carcinogenesis 08/2011 - 01/2005
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2011 - 01/2004
2	Carcinoma (Carcinomatosis) 10/2008 - 01/2005
1	Bone Resorption 03/2017
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2017
1	Alveolar Bone Loss 03/2016
1	Melanoma (Melanoma, Malignant) 04/2015
1	Rheumatoid Arthritis 03/2013
1	Aneuploidy (Aneuploid) 01/2013
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/2012
1	Neuroblastoma 12/2011
1	Body Weight (Weight, Body) 11/2011
1	Weight Gain 11/2011
1	Peritoneal Neoplasms 05/2011

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2004
7	Messenger RNA (mRNA)IBA 04/2017 - 06/2008
7	Connective Tissue Growth FactorIBA 07/2015 - 03/2004
6	IntegrinsIBA 07/2015 - 03/2004
4	Insulin-Like Growth Factor II (Somatomedin A)IBA 04/2015 - 10/2008
4	Carrier Proteins (Binding Protein)IBA 04/2015 - 10/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2013 - 01/2004
4	Cysteine (L-Cysteine)FDA Link 06/2008 - 08/2005
3	Interleukin-6 (Interleukin 6)IBA 03/2017 - 06/2007
3	MicroRNAs (MicroRNA)IBA 01/2017 - 09/2013
3	Small Interfering RNA (siRNA)IBA 09/2016 - 08/2011
3	CalreticulinIBA 05/2014 - 02/2009
3	NF-kappa B (NF-kB)IBA 02/2009 - 06/2004
2	SirtuinsIBA 03/2017 - 03/2013
2	Plasminogen Activators (Plasminogen Activator)IBA 12/2016 - 06/2008
2	CateninsIBA 12/2016 - 09/2016
2	ChromatinIBA 01/2016 - 09/2011
2	Chemokine ReceptorsIBA 11/2013 - 11/2007
2	Simvastatin (Zocor)FDA LinkGeneric 03/2013 - 04/2011
2	Cysteine-Rich Protein 61IBA 03/2013 - 11/2007
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 10/2011 - 10/2008
2	Protein Isoforms (Isoforms)IBA 08/2011 - 01/2004
2	CytokinesIBA 04/2011 - 06/2007
2	Vascular Endothelial Growth Factor CIBA 10/2008 - 01/2004
2	Liposomes (Liposome)IBA 11/2007 - 08/2005
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2005 - 01/2004
1	Lactate Dehydrogenase 5IBA 03/2017
1	Lactic Acid (Lactate)FDA LinkGeneric 03/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2017
1	Glucose (Dextrose)FDA LinkGeneric 03/2017
1	Histone Deacetylases (Histone Deacetylase)IBA 03/2017
1	Fructose-Bisphosphate Aldolase (Aldolase)IBA 01/2016
1	EnzymesIBA 01/2016
1	Complement C1r (Complement Component 1r)IBA 12/2015
1	Laminin (Merosin)IBA 07/2015
1	Cell Adhesion MoleculesIBA 07/2015
1	mouse MIRN29 microRNAIBA 02/2015
1	Galactoside 2-alpha-L-fucosyltransferase (Fucosyltransferase 2)IBA 05/2014
1	RNA (Ribonucleic Acid)IBA 09/2013
1	Cadherins (E-Cadherin)IBA 07/2013
1	Oncogene Proteins (Oncogene Protein)IBA 07/2013
1	Sirtuin 1IBA 03/2013
1	Aurora Kinase AIBA 01/2013
1	Therapeutic UsesIBA 01/2013
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2012
1	CXCR4 Receptors (CXCR4 Receptor)IBA 06/2012
1	Interleukin-8 (Interleukin 8)IBA 06/2012
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2011
1	Lysine (L-Lysine)FDA Link 09/2011
1	Histones (Histone)IBA 09/2011
1	histone deacetylase 3IBA 09/2011
1	Histone MethyltransferasesIBA 09/2011
1	collapsin response mediator protein-1IBA 08/2011
1	Histone Deacetylase InhibitorsIBA 08/2011
1	Histone Deacetylase 2IBA 08/2011
1	Cisplatin (Platino)FDA LinkGeneric 09/2010
1	Complementary DNA (cDNA)IBA 02/2009
1	Chemokine CXCL12IBA 02/2009
1	Biological ProductsIBA 11/2008

Therapy/Procedure

5	Therapeutics 01/2017 - 01/2005
1	Precision Medicine 01/2017
1	Intra-Articular Injections 03/2013
1	Craniotomy 01/2013
1	Intraperitoneal Injections 05/2011
1	Drug Therapy (Chemotherapy) 09/2010